Illinois pharmacists were surveyed to identify predictors of their work-related attitudes. A survey was mailed in April 1994 to 600 Illinois pharmacists to identify their attitudes about their career, the organization where they work, and the impact of national health care reform and the pharmaceutical care movement on the future of pharmacy. The survey also collected information on the respondents' work site and position; coworkers, family, and friends; and demographic characteristics. The survey was completed by 337 pharmacists. Pharmacists who believed that pharmaceutical care would have a more positive effect on pharmacy were more committed to their employer and to pharmacy as a career. Co-worker support had a positive effect on perceptions about pharmaceutical care, and supervisor support increased career and organizational commitment. Age did not affect career or organizational commitment, but it did negatively affect pharmacists' views of the impact that the call for pharmaceutical care would have on pharmacy. Hospital pharmacists were less committed than community pharmacists to the organizations where they worked. Practice setting, supervisor support, and perceptions about the impact of the pharmaceutical care movement were identified as possible predictors of career and organizational commitment.