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KRISTI M. KUPER, PHARMD., BCPS, is Clinical Director, Infectious. Disease, Department of Clinical Affairs, Cardinal Health, Houston, TX. ELIZABETH B. HIRSCH, PHARM.D., is Pharmacy Infectious Diseases Fellow, Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Houston, and Department of Pharmacy, St. Luke’s Episcopal Hospital, Houston. VINCENT H. TAM, PHARMD., BCPS, is Associate Professor, Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston.

Address correspondence to Dr. Kuper at the Department of Clinical Affairs, Cardinal Health, 1330 Enclave Parkway, Houston, TX 77077 (kristine.kuper{at}cardinalhealth.com).

Purpose. Significant publications on infectious diseases (ID) pharmacotherapy in 2008 were compiled and summarized. Summary. On December 31, 2008, the Houston Infectious Diseases Network compiled a listing of published articles identified as having a significant impact on ID pharmacotherapy. The publication period was limited to January 1 through December 31, 2008. Articles were selected based on prior presentations at ID and pharmacy meetings or were listed as major articles in prominent ID journals. Priority was given to articles that were published in peer-reviewed journals and to treatment guidelines endorsed by major medical and pharmacy organizations. A bibliography of 56 articles (40 not related to human immunodeficiency virus [HIV] infection and 16 related to HIV infection) was distributed to members of the Society of Infectious Diseases Pharmacists (SIDP) via an Internet survey in early January 2009. Members were asked to select 10 publications not related to HIV infection and 1 HIV-related publication that they believed made the greatest contribution to the antimicrobial-related medical literature in 2008. A total of 115 SIDP members participated in the survey. Summaries of the top articles selected, along with an interpretation of their effect on clinical practice, are included. Conclusion. The increasing number of articles in the peer-reviewed medical literature related to the diagnosis and treatment of ID has made it challenging to maintain a contemporary knowledge base of key publications. This summary of significant ID articles published in 2008 can help to alleviate this burden. Index terms: Antiinfective agents; Communicable diseases; Publications

 

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